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1.
Artigo em Espanhol | LILACS, BDNPAR | ID: biblio-1337596

RESUMO

La periodontitis crónica es una patología caracterizada por la destrucción de los tejidos de soporte del diente. Existe evidencia científica de la presencia en bolsas periodontales de Pseudomonas aeruginosa, bacteria que altera la microbiota subgingival. Ha sido asociada al fracaso en el tratamiento de la periodontitis y podría constituir un riesgo para la salud general de los pacientes. El objetivo de esta investigación fue determinar la frecuencia de P. aeruginosa en bolsas periodontales de pacientes con periodontitis crónica que acudieron a la cátedra de Periodoncia de la Universidad Autónoma de Asunción. El estudio fue observacional descriptivo de corte transversal, para el mismo fueron seleccionados pacientes con periodontitis crónica que cumplían con los criterios de inclusión. Las piezas dentariasseleccionadas para la toma de muestras fueron aisladas con rollos de algodón estéril, y una vez removida la placa bacteriana supragingival, se retiró la placa subgingival de las bolsas periodontales por medio de curetas de Gracey y se introdujeron en tubos de ensayo que contenían medio de Stuart, para luego llevar las muestras hasta el laboratorio de microbiología para su análisis. Del total de 14 muestras, solo una dio positivo a P. aeruginosa representando el 7,14%. El microrganismo aislado resultó resistente a los antibióticos utilizados como coadyuvantes en el tratamiento de la periodontitis crónica,al igual que en otros trabajos encontrados en la literatura internacional. La presencia de estas bacterias dificulta el control de la enfermedad periodontal y podría significar un riesgo para desarrollar infecciones oportunistas, especialmente en los pacientes inmunodeprimidos


Chronic periodontitis is a pathology characterized by the destruction of tooth supporting tissues. There is scientific evidence of the presence in periodontal pockets of Pseudomonas aeruginosa, a bacterium that alters the subgingival microbiota and that has been associated with failure to treat periodontitis and could constitute a risk to patient general health. The objective of this research was to determine the frequency of P. aeruginosa in periodontal pockets of patients with chronic periodontitis who attend the Chair of Periodontology at the Autonomous University of Asunción. Descriptive, cross-sectional observational study, in which patients with chronic periodontitis who met the inclusion criteria were selected. The pieces selected for sampling were isolated with sterile cotton rolls, and once the supragingival bacterial plaque had been removed, the subgingival plaque was removed from the periodontal pockets by means of Gracey curettes and placed in test tubes containing Stuart medium, then the samples were taken to the microbiology lab for analysis. Of the total of 14 samples, only one was positive for P. aeruginosa, representing 7.14%. The isolated microorganism was resistant to the antibiotics used as adjuvants in the treatment of chronic periodontitis, as in other studies found in the international literature. The presence of these bacteria makes it difficult to control periodontal disease and could pose a risk for developing opportunistic infections, especially in immunosuppressed patients


Assuntos
Humanos , Masculino , Feminino , Abscesso Periodontal/microbiologia , Pseudomonas aeruginosa , Periodontite Crônica , Curetagem Subgengival
2.
Sci Rep ; 10(1): 16322, 2020 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-33004857

RESUMO

Nonsurgical periodontal therapy with adjunctive use of systemic antimicrobials (for 7-14 days) showed improved clinical, microbiological and immunological results over the mechanical protocol alone. Considering the increasing risk for antimicrobial resistance with longer antibiotic regimes, it is important to establish the optimal antibiotic protocol with a maximum antimicrobial benefit and minimum risk for adverse effects. The aim of the study was to evaluate the microbiological and inflammatory outcomes 12-months after a 3-/7-day systemic antibiotic protocol [amoxicillin (AMX) + metronidazole (MET)] adjunctive to subgingival debridement in severe periodontitis compared to mechanical treatment alone. From the initially treated 102 patients, 75 subjects (Placebo group: n = 26; 3-day AMX + MET group: n = 24; 7-day AMX + MET group: n = 25) completed the 12-month examination. Clinical parameters, eight periodontal pathogens and inflammatory markers were determined at baseline and 3-, 6-, 12-months after therapy using real-time PCR and ELISA respectively. After 6 months, several periodontopathogens were significantly more reduced in the two antibiotic groups compared to placebo (p < 0.05). After 1 year, both antibiotic protocols showed significant reductions and detection of the keystone pathogen P. gingivalis compared to placebo. Antibiotic protocols, smoking, disease severity, baseline-BOP, -CAL and -IL-1ß, as well as detection of T. denticola at 12-months significantly influenced the residual number of deep sites. The present data indicate that the systemic use of both short and longer antibiotic protocols (AMX + MET) adjunctive to nonsurgical periodontal therapy lead to higher microbiological improvements compared to subgingival debridement alone. The two investigated antibiotic protocols led to comparable microbiological and inflammatory results.


Assuntos
Amoxicilina/uso terapêutico , Anti-Infecciosos/uso terapêutico , Metronidazol/uso terapêutico , Periodontite/terapia , Adulto , Aggregatibacter actinomycetemcomitans , Amoxicilina/administração & dosagem , Anti-Infecciosos/administração & dosagem , Biomarcadores , Esquema de Medicação , Quimioterapia Combinada , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Masculino , Metronidazol/administração & dosagem , Periodontite/tratamento farmacológico , Periodontite/microbiologia , Porphyromonas gingivalis , Reação em Cadeia da Polimerase em Tempo Real , Curetagem Subgengival/métodos
3.
Clin Exp Dent Res ; 6(4): 470-477, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32573120

RESUMO

OBJECTIVE: This study aimed to analyze the effectiveness of root-shape inserts mounted on a reciprocating handpiece during the procedure of root surface debridement (RSD) on extracted teeth. Three different approaches were compared: ultrasonic scaling, employment of root-shape inserts mounted on a reciprocating handpiece, and a combination of both. MATERIALS AND METHODS: A total of 51 extracted teeth were divided into three groups. The first group was instrumented with an ultrasonic scaler, the second group with flexible root-shape inserts mounted on a reciprocating handpiece (grain size 40, 15, and 4 µm), whereas the final group underwent a combination of both approaches. The time required for the instrumentation was taken. The specimens were subjected to optical and scanning electron microscopy (SEM), and the photographs were evaluated by three examiners who were blinded to the study. The parameters included were: SEM roughness index (SRI) for the roughness calculation, remaining calculus Index (RCI) to evaluate the residual calculus deposits, and loss of tooth substance index (LTSI) to evaluate the loss of tooth substance caused by instrumentation. RESULT: The results revealed that the time taken for the instrumentation was on average longer when the root-shape inserts were employed alone, meanwhile the combined approach did not show significant difference in comparison with the ultrasonic scaling. The lower average RCI was obtained with a combined approach. The use of root-shape inserts seems to cause a moderate increase in LTSI, especially in a combined approach, whereas it resulted in a better average SRI. CONCLUSION: The employment of root-shape inserts seems to be effective in the RSD for its ability to obtain a smooth and calculus-free instrumented surface, especially when used in combination with an ultrasonic scaler, and their use can so represent a valid approach to be tested in further in vivo studies.


Assuntos
Microscopia Eletrônica de Varredura/métodos , Desbridamento Periodontal/métodos , Doenças Periodontais/terapia , Aplainamento Radicular/métodos , Curetagem Subgengival/métodos , Raiz Dentária/cirurgia , Ultrassom/métodos , Raspagem Dentária/instrumentação , Humanos , Doenças Periodontais/patologia , Aplainamento Radicular/instrumentação , Extração Dentária/métodos , Raiz Dentária/ultraestrutura
4.
Int J Dent Hyg ; 16(4): 553-558, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29797806

RESUMO

OBJECTIVES: The aim of this study was to investigate the morphological and surface roughness changes in dental root samples following periodontal scaling by hand curette, piezoelectric ultrasonic devices or a combination of these. METHODS: Twenty-four monoradicular teeth extracted as a result of periodontal disease were divided into 4 groups: Group A was treated by piezoelectric ultrasonic scaler Piezon® Master 400; Group P by piezoelectric ultrasonic scaler PiezoSmart® ; Group C using Gracey curette 7/8; Group AC by a combined technique of piezoelectric ultrasonic scaler Piezon® Master 400 and Gracey curette 7/8. The treated samples were then analysed using a white light interferometer and scanning electron microscopy (SEM). RESULTS: Roughness analysis revealed major surface alterations in Group C (Sa  = 24.98 µm); the samples treated using the combined technique (Group AC) showed reduced but still significant alteration (Sa  = 14.48 µm), while samples treated with the piezoelectric ultrasonic devices (Group A and Group P) presented the lowest roughness values (Sa  = 8.99 and Sa  = 4.45 µm, respectively). A significant difference was found between groups C and P (P = 0.036). SEM analysis confirmed the roughness analysis revealing non-homogeneous surfaces in Group C, while a less morphological alteration was noted in the other groups. CONCLUSION: All periodontal devices used in this in vitro study produced a certain degree of surface alteration. Hand curettes appear to have a major impact on surface integrity compared with piezoelectric ultrasonic devices.


Assuntos
Cálculos Dentários/terapia , Raspagem Dentária/instrumentação , Ondas de Choque de Alta Energia , Curetagem Subgengival/instrumentação , Raiz Dentária/patologia , Raiz Dentária/ultraestrutura , Raspagem Dentária/métodos , Humanos , Microscopia Eletrônica de Varredura , Aplainamento Radicular/instrumentação , Curetagem Subgengival/efeitos adversos , Propriedades de Superfície
5.
J Formos Med Assoc ; 117(11): 1003-1010, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29174174

RESUMO

BACKGROUND/PURPOSE: Chronic periodontitis (CP) and rheumatoid arthritis (RA) are the most common chronic inflammatory diseases and their immunopathogenesis is similar. The aim of this study was to evaluate the effect of non-surgical periodontal treatment on the serum levels of RA-related inflammatory markers in patients with chronic periodontitis. METHODS: Thirty-one Taiwanese adults with CP were included. Demographics and periodontal parameters, including probing depth, clinical attachment level, and number of remaining teeth in the oral cavity, were recorded. All subjects received non-surgical periodontal treatment such as scaling and subgingival root planing. Serum samples were collected before and after the treatment. Serum levels of anti-citrullinated protein antibodies (ACPA), rheumatoid factor, tumor necrosis factor-α (TNF-α), C-reactive protein, interleukin-1ß (IL-1ß), and Interleukin-6 (IL-6) were measured using an enzyme-linked immunosorbent assay. RESULTS: Non-surgical periodontal treatment significantly reduced the serum ACPA (p = 0.015) and TNF-α levels (p = 0.026) in CP patients, particularly in patients with generalized CP. Furthermore, there was a significant and positive correlation between the number of extracted teeth and the reduction in the serum ACPA (p = 0.05) and IL-1ß levels (p = 0.029) after non-surgical periodontal treatment. CONCLUSION: Non-surgical periodontal therapy may aid in the control of RA-related inflammatory markers in patients with CP. A large-scale study with well-defined populations is needed to clarify the benefit of non-surgical periodontal therapy.


Assuntos
Artrite Reumatoide/sangue , Biomarcadores/sangue , Periodontite Crônica/sangue , Periodontite Crônica/terapia , Raspagem Dentária , Curetagem Subgengival , Adulto , Anticorpos Antiproteína Citrulinada/sangue , Feminino , Humanos , Interleucina-1beta/sangue , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Fator de Necrose Tumoral alfa/sangue
6.
Periodontol 2000 ; 76(1): 164-179, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29197129

RESUMO

Treatment of periodontitis aims to control the infection caused by the periodontal pathogenic flora and includes mechanical debridement of root surfaces to disrupt the supragingival and subgingival biofilm. As periodontal pockets of ≤ 5 mm can be perform in a stable condition and may not need additional therapy, the ability and the willingness of the patient to perform good oral hygiene on a long-term basis are of utmost importance for ensuring long-term success of periodontal treatment. In this context, the aim of all home-care measures must be the optimal control of plaque biofilm in order to prevent or treat gingival inflammation as a primary stage of periodontitis. Despite the fact that toothbrushing and other mechanical cleaning practices are the most important elements for preventing periodontal diseases or their progression, other factors, including education, motivation, manual dexterity and compliance with professional recommendation, provision of time and socio-economic status, as well as risk factors, play a role. The present article provides an overview on the various possibilities for self-care of residual pockets in patients with periodontitis.


Assuntos
Bolsa Periodontal/terapia , Periodontite/terapia , Autocuidado/métodos , Antibacterianos/uso terapêutico , Biofilmes , Clorexidina , Assistência Odontológica , Profilaxia Dentária , Escolaridade , Gengivite/terapia , Humanos , Motivação , Higiene Bucal/métodos , Doenças Periodontais/terapia , Fatores de Risco , Autocuidado/psicologia , Fumar , Classe Social , Curetagem Subgengival/métodos , Escovação Dentária
7.
Periodontia ; 28(4): 57-68, 2018.
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-980356

RESUMO

A proposta desta revisão da literatura foi avaliar as técnicas empregadas no afastamento gengival para prótese dental incluindo métodos mecânicos, químicos-mecânicos e cirúrgicos. A técnica de afastamento gengival deve ser previamente avaliada pelo profissional e a sua indicação, dependerá de cada situação clínica. Nesta revisão foram apresentadas as vantagens e desvantagens das técnicas de afastamento gengival incluindo fio afastador embebido ou não em soluções químicas, técnicas cirúrgicas, procedimentos a base de laser, curetagem gengival e eletro cirurgia. Após a realização desta revisão verificamos que o método químico-mecânico é o mais utilizado pelos profissionais. Atualmente podemos considerar que mesmo com a utilização de tecnologias mais elaboradas, como por exemplo scanners intraorais, quando o término do preparo dental estiver ao nível gengival ou subgengival se faz necessário o afastamento gengival. Para atingir o sucesso de uma prótese dental e importante coexistir uma harmonia entre a prótese e os tecidos periodontais circunvizinhos. (AU)


The aim of this review was to assess the use of gingival retraction methods in the fixed tooth supported prosthesis including mechanical, chemicals-mechanical and surgical methods. The choice of the best gingival retraction technique should be considered previously by the professional and it depends of each individual clinical conditions. In this review were discussed the advantages and the disadvantages of each gingival retraction technique including mechanical, chemical and surgical methods. In this review, we could understand that chemicals-mechanical technical is the most indicate by dentists. Nowadays, we can consider that even with the hightech use in dental area, such as intraoral scanners, when the margin of the restoration is placed sub-gingivally the gingival retraction should be considered. For the successful in dental prosthesis, a healthy coexistence between the restoration and their surrounding periodontal structure should be the goal of a prosthodontist. (AU)


Assuntos
Curetagem Subgengival , Saúde Bucal , Aumento da Coroa Clínica , Prótese Dentária , Gengiva
8.
Sci Rep ; 7(1): 16122, 2017 11 23.
Artigo em Inglês | MEDLINE | ID: mdl-29170383

RESUMO

Humans have a strong need to belong to social groups and a natural inclination to benefit ingroup members. Although the psychological mechanisms behind human prosociality have extensively been studied, the specific neural systems bridging group belongingness and altruistic motivation remain to be identified. Here, we used soccer fandom as an ecological framing of group membership to investigate the neural mechanisms underlying ingroup altruistic behaviour in male fans using event-related functional magnetic resonance. We designed an effort measure based on handgrip strength to assess the motivation to earn money (i) for oneself, (ii) for anonymous ingroup fans, or (iii) for a neutral group of anonymous non-fans. While overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three conditions, the subgenual cingulate cortex (SCC) exhibited increased functional connectivity with the mOFC as well as stronger hemodynamic responses for ingroup versus outgroup decisions. These findings indicate a key role for the SCC, a region previously implicated in altruistic decisions and group affiliation, in dovetailing altruistic motivations with neural valuation systems in real-life ingroup behaviour.


Assuntos
Altruísmo , Motivação/fisiologia , Recompensa , Futebol , Adulto , Encéfalo/diagnóstico por imagem , Encéfalo/fisiologia , Empatia/fisiologia , Feminino , Força da Mão/fisiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Córtex Pré-Frontal/diagnóstico por imagem , Córtex Pré-Frontal/fisiologia , Comportamento Social , Curetagem Subgengival
9.
Artigo em Inglês | MEDLINE | ID: mdl-29023608

RESUMO

The aim of this study was to retrospectively evaluate the periodontal response of periodontally healthy teeth prosthetically restored using a featheredge finish line preparation combined with a light rotary curettage (gingittage). A total of 137 restored teeth were included in the study. Mean follow-up time was 18.2 months (range: 6 to 60 months). Bleeding on probing was noted in 18% of cases, while the Plaque Index was found to be 11%. The probing depth in 99.4% of cases was ≤ 3 mm. In only 7 cases (5.1%), a slight restoration margin exposure was recorded. Although randomized controlled studies with longer follow-up are advocated, the present investigation seems to suggest that this protocol is a viable procedure.


Assuntos
Prótese Dentária , Periodonto , Curetagem Subgengival , Adulto , Idoso , Idoso de 80 Anos ou mais , Instrumentos Odontológicos , Índice de Placa Dentária , Desenho de Equipamento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice Periodontal , Estudos Retrospectivos
10.
Pathog Dis ; 75(7)2017 09 29.
Artigo em Inglês | MEDLINE | ID: mdl-28859277

RESUMO

This study aimed to evaluate the association between haplotypes in the interleukin 8 (IL8) and IL4 genes previously associated to chronic periodontitis (CP) and the levels of Aggregatibacter actinomycetemcomitans (A.a.) in subgingival sites of patients with and without CP. Moreover, multifaceted evaluations were made to search associations among patients' genetic background with the A.a. levels and previous clinical/immunological/microbiological findings. Subgingival sites (n = 596) of 104 patients were divided into susceptible to CP by the IL8 haplotype ATC/TTC (IL8+); non-susceptible to CP by the IL8 AGT/TTC (IL8-); susceptible to CP by the IL4 TCI/CCI (IL4+); protection against CP by the IL4 TTD/CTI (IL4-). Subgingival biofilm samples from diseased and healthy sites of CP patients and from control sites of health patients were obtained for absolute quantification of A.a. by quantitative real-time polymerase chain reaction. For diseased sites, samples were collected before and 45 days after periodontal treatment. The IL4 but not the IL8 haplotypes were associated with levels of A.a. (in both periods). After periodontal treatment, higher levels of A.a. were found in subgingival sites of (IL4-) patients, and higher levels of IL-4 were associated with deeper probing pockets in these same patients. Significant correlations were found among genetic (patients carrying IL8 or IL4 haplotypes), microbiological and immunological data showing the interrelationship of different factors in the CP.


Assuntos
Aggregatibacter actinomycetemcomitans/genética , Biofilmes/crescimento & desenvolvimento , Periodontite Crônica/genética , Predisposição Genética para Doença , Interleucina-4/genética , Interleucina-8/genética , Polimorfismo Genético , Adulto , Aggregatibacter actinomycetemcomitans/crescimento & desenvolvimento , Aggregatibacter actinomycetemcomitans/isolamento & purificação , Aggregatibacter actinomycetemcomitans/patogenicidade , Carga Bacteriana , Periodontite Crônica/imunologia , Periodontite Crônica/microbiologia , Periodontite Crônica/terapia , Feminino , Expressão Gênica , Haplótipos , Humanos , Interleucina-4/imunologia , Interleucina-8/imunologia , Masculino , Pessoa de Meia-Idade , Análise Multivariada , RNA Ribossômico 16S/genética , Curetagem Subgengival
11.
Photodiagnosis Photodyn Ther ; 18: 331-334, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28457847

RESUMO

OBJECTIVE: The aim of the present 12-weeks follow-up randomized clinical trial was to investigate the outcome of mechanical curettage (MC) with or without adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri-implant mucositis in cigarette smokers. METHODS: Therapeutically, subjects with peri-implant mucositis were divided into 2 groups: (a) Group-A: MC+aPDT; and (b) Group-B: MC alone (control group). In both groups, peri-implant plaque index (PI), bleeding on probing (BOP) and probing pocket depth (PPD) were gauged at baseline and after 12-weeks follow-up. Group comparisons were performed using the Kruskall-Wallis test. P-values less than 0.05 were considered statistically significant. RESULTS: Fifty-four male patients (28 in Group-A and 26 in Group-B) were included. The mean age of individuals in groups A and B were 50.6±0.8 and 52.2±0.5years, respectively. In groups A and B the participants were smoking 16.5±2.7 and 14.2±1.7 cigarettes daily since 25.2±6.5 and 24.6±4.3years, respectively. Periimplant PI, BOP and PPD were comparable among individuals in both groups at baseline. At 12-weeks follow-up, there was a significant reduction in PI (P<0.001) and PPD (P<0.001) among patients in groups A and B compared with their respective baseline values. At 12-weeks follow-up, PI (P<0.001) and PPD (P<0.001) were significantly higher among patients in Group-B compared with Group-A (P<0.001). BOP was comparable in both groups at baseline and at 12-weeks follow-up. CONCLUSION: In cigarette smokers, MC with adjunct aPDT is more effective in the treatment of peri-implant mucositis compared with MC alone.


Assuntos
Fumar Cigarros/efeitos adversos , Peri-Implantite/etiologia , Peri-Implantite/terapia , Fotoquimioterapia/métodos , Estomatite/etiologia , Estomatite/terapia , Curetagem Subgengival/métodos , Adulto , Terapia Combinada/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
12.
Intern Med ; 56(9): 1015-1021, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28458305

RESUMO

Objective Periodontal disease may predispose individuals to cardiovascular disease (CVD). Diabetes mellitus, especially in patients with severe periodontitis, increases the risk of CVD mortality. However, the outcomes of periodontal therapy vary among the different treatment modalities. We aim to investigate whether periodontal treatment could influence the occurrence of CVD in patients with type 2 diabetes and periodontal problems. Methods A retrospective cohort study was conducted based on a dataset released by Taiwan National Health Insurance (NHI). The dataset was composed of randomly sampled, newly diagnosed diabetic patients who received insurance benefits from 1999 to 2001; patients who were younger than 18 years of age or who already had CVD before 1999 were excluded. The NHI code was used to identify the treatments, including subgingival curettage and flap operations. The patients' demographic variables were matched using a 1:4 propensity score. All of the subjects were followed up until the onset of CVD, or December 31, 2011. A Cox proportional hazards regression analysis was performed to evaluate the effects of periodontal treatment on the rates of myocardial infarction, heart failure and stroke. Results Three thousand thirty-nine and 12,156 diabetic subjects were classified into the advanced periodontal treatment group and the non-advanced periodontal treatment group, respectively. The Cox proportional hazards analysis revealed that although the overall incidence of CVD was not significantly improved (Hazard ratio, HR 0.95; 95% CI 0.90-1.01), advanced periodontal treatment reduced the rates of myocardial infarction (HR 0.92; 95% CI 0.85-0.99) and heart failure (HR 0.60; 95% CI 0.45-0.80). There was no significance difference in the incidence of stroke (HR 0.95; 95% CI 0.85-1.06). Conclusion Advanced periodontal therapy lowers the rate of CVD, especially myocardial infarction and heart failure. Dental management has a beneficial effect on the health of patients with type 2 diabetes.


Assuntos
Doenças Cardiovasculares/etiologia , Diabetes Mellitus Tipo 2/complicações , Periodontite/terapia , Curetagem Subgengival/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Cardiovasculares/epidemiologia , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Pontuação de Propensão , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Fatores de Risco , Fatores Socioeconômicos , Taiwan/epidemiologia , Adulto Jovem
13.
Photodiagnosis Photodyn Ther ; 18: 260-263, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28347865

RESUMO

OBJECTIVE: The aim was to investigate the effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjuvant to mechanical curettage (MC) in the treatment of periimplant mucositis in smokeless tobacco (ST) product users. METHODS: Forty-eight ST product users with periimplant mucositis were randomly divided into 2 groups. In the test-group, participants underwent periimplant MC with adjunct aPDT; and in the control-group, the patients underwent MC alone. Periimplant plaque index (PI), bleeding on probing (BOP), and probing depth (PD) were measured at baseline and after 3-months of follow-up. Statistical analysis was performed using the Kruskal-Wallis test. Level of significance was set at P<0.05. RESULTS: At baseline, periimplant PI, BOP and PD were comparable among individuals in the test- and control groups. At 3-months follow-up, scores of periimplant PI (P<0.05), BOP (P<0.05) and PD (P<0.05) were statistically significantly higher among patients in the control-group compared with the test-group. At 3-months follow-up, the percentages of sites of PI, BOP and PD were statistically significantly higher in the control-sites as compared to the test-sites. CONCLUSION: Among patients with periimplant mucositis, MC with adjunct aPDT is more effective in reducing periimplant inflammation in ST product users as compared to MC alone; however, the present result should be interpreted with caution as they were based on a short-term follow-up. Further long-term studies are needed in this regard.


Assuntos
Peri-Implantite/etiologia , Peri-Implantite/terapia , Fotoquimioterapia/métodos , Estomatite/etiologia , Estomatite/terapia , Curetagem Subgengival/métodos , Tabaco sem Fumaça/efeitos adversos , Adulto , Terapia Combinada/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
14.
J Periodontal Res ; 52(1): 74-82, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26957231

RESUMO

BACKGROUND AND OBJECTIVE: The barrier function of long junctional epithelium is thought to be important after periodontal initial therapy and periodontal surgery. Although the difference between long junctional epithelium and normal junctional epithelium regarding their resistance to destruction of periodontal tissue has been investigated, the mechanism still remains unclear. Using our rat experimental periodontitis model in which loss of attachment and resorption of alveolar bone is induced by the formation of immune complexes, we investigated the resistance of periodontal tissue containing long junctional epithelium and normal junctional epithelium to destruction. MATERIAL AND METHODS: Rats were divided into four groups. In the immunized long junctional epithelium (I-LJE) group, rats were immunized with lipopolysaccharide (LPS), and curettage and root planing procedures were performed on the palatal gingiva of the maxillary first molars to obtain reattachment by long junctional epithelium. In the immunized normal junctional epithelium (I-JE) group, rats were immunized without curettage and root planing procedures. In the nonimmunized long junctional epithelium (nI-LJE) group, rats were not immunized but curettage and root-planing procedures were performed. In the control group, neither immunization nor curettage and root-planing was performed. In all rats, periodontal inflammation was induced by topical application of LPS into the palatal gingival sulcus of maxillary first molars. The rats were killed at baseline and after the third and fifth applications of LPS. Attachment loss and the number of inflammatory cells and osteoclasts in the four groups were compared histopathologically and histometrically. RESULTS: After the third application of LPS in the I-LJE group, attachment loss showed a greater increase than in control and nI-LJE groups, and inflammatory cell infiltration and osteoclasts were increased more than in the other groups. After the fifth application of LPS, attachment loss was greater and there was a higher degree of inflammatory cell infiltration in nI-LJE and I-LJE groups than in control and I-JE groups. CONCLUSION: Our findings suggest that the destruction of periodontal tissue is increased in tissue containing long junctional epithelium compared with normal junctional epithelium and that the immunized condition accelerates the destruction by forming immune complexes.


Assuntos
Inserção Epitelial/patologia , Periodonto/patologia , Animais , Modelos Animais de Doenças , Ensaio de Imunoadsorção Enzimática , Gengiva/patologia , Masculino , Ratos , Ratos Endogâmicos Lew , Aplainamento Radicular , Curetagem Subgengival
15.
Photodiagnosis Photodyn Ther ; 15: 191-6, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27344944

RESUMO

BACKGROUND: The aim of the present study was to review the pertinent literature on the effects of mechanical curettage (MC) with and without adjunct photodynamic therapy (PDT) for the management of peri-implantitis. METHODS: The addressed focused question was "Is PDT effective in the treatment of peri-implantitis?" A search without language or time restrictions up to March 2016 was conducted using various key words. The exclusion criteria included; review papers, in vitro Studies, case reports, commentaries, interviews, and letters to the editors. RESULTS: In total 9 studies were included. Among them 5 studies were clinical and 4 were experimental. All the studies used PDT as an adjunctive to MC in their test groups. The laser wavelengths used ranged from 660nm to 830nm. One study showed significant reduction of the bleeding scores, inflammatory exudates and Aggregatibacter actinomycetemcomitans count in group with PDT as an adjunctive when compared to MC and 0.2% chlorhexidine. However, in four clinical studies comparable periodontal parameters were reported when PDT is used as an adjunct to MC was compared to MC in treatment of peri-implantitis. In three experimental studies, outcomes were significantly better in group with PDT as an adjunct to MC when compared to MC alone at follow-up. CONCLUSION: The role of PDT as an adjunct to MC in the treatment of peri-implantitis is debatable. Further longterm randomised control trails are needed to justify the role PDT as an adjunct to MC in treatment of peri-implantitis.


Assuntos
Infecções Bacterianas/epidemiologia , Infecções Bacterianas/terapia , Peri-Implantite/epidemiologia , Peri-Implantite/terapia , Fotoquimioterapia/estatística & dados numéricos , Curetagem Subgengival/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Infecções Bacterianas/diagnóstico , Quimiorradioterapia Adjuvante/estatística & dados numéricos , Cães , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Peri-Implantite/diagnóstico , Prevalência , Coelhos , Fatores de Risco , Resultado do Tratamento
16.
Medicine (Baltimore) ; 95(20): e3735, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27196497

RESUMO

Treatment of periodontal diseases has been associated with benefit outcomes for patients with chronic obstructive pulmonary disease (COPD). However, no population-based cohort study has been conducted. We evaluated this relationship by retrospective cohort study using a large population data.Using the National Health Insurance claims data of Taiwan, we identified 5562 COPD patients with periodontal diseases who had received periodontal treatment as the treatment group. The comparison group was selected at a 1:1 ratio matched by the propensity score estimated with age, sex, date of COPD diagnosis and periodontal treatment, and comorbidities. Both groups were followed up for 5 years to compare risks of acute exacerbation, pneumonia, and acute respiratory failure.The incidence rates of adverse respiratory events were significantly lower in the treatment group than in the comparison group: 3.79 versus 4.21 per 100 person-years for emergency room visits, 2.75 versus 3.65 per 100 person-years for hospitalizations, and 0.66 versus 0.75 per 100 person-years for intensive care unit admissions. The treatment group also had a 37% reduced risk of deaths (1.81 vs 2.87 per 100 person-years), with an adjusted hazard ratio of 0.57 (95% confidence interval 0.52-0.62).Periodontal treatment for COPD patients could reduce the risk of adverse respiratory events and mortality. The adequate periodontal health care is important for COPD patients with periodontal diseases.


Assuntos
Doenças Periodontais/complicações , Doenças Periodontais/terapia , Pneumonia/epidemiologia , Doença Pulmonar Obstrutiva Crônica/complicações , Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Insuficiência Respiratória/epidemiologia , Idoso , Progressão da Doença , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Pontuação de Propensão , Fatores de Proteção , Doença Pulmonar Obstrutiva Crônica/mortalidade , Curetagem Subgengival , Taiwan/epidemiologia
17.
Periodontol 2000 ; 71(1): 128-39, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27045434

RESUMO

A renewed interest in conservative surgical techniques has been fueled by new technology, changes in referral patterns to periodontists and a desire to achieve periodontal health in the least invasive, most cost-efficient manner possible. Trends suggest that an increasing amount of periodontal care is being provided in the offices of general dentists. If true, it is likely that patients receiving care in these offices will be offered simpler surgical treatment modalities that do not require an extensive armamentarium. The purpose of this article was to review the effectiveness of six relatively simple surgical techniques - gingivectomy, flap debridement, modified Widman flap, excisional new attachment procedure, modified excisional new attachment procedure and laser-assisted new attachment procedure - and to compare the results obtained using these procedures with the well-known clinical benefits of scaling and root planing. The intent was to determine whether the benefits of surgical procedures in the hands of most general dentists extend beyond those of conventional nonsurgical therapy.


Assuntos
Periodontite Crônica/cirurgia , Periodontite Crônica/terapia , Raspagem Dentária/métodos , Aplainamento Radicular/métodos , Tratamento Conservador/métodos , Raspagem Dentária/economia , Gengivectomia/métodos , Humanos , Terapia a Laser/métodos , Desbridamento Periodontal/métodos , Aplainamento Radicular/economia , Curetagem Subgengival/métodos , Retalhos Cirúrgicos
18.
Fogorv Sz ; 109(4): 125-135, 2016 Dec.
Artigo em Inglês, Húngaro | MEDLINE | ID: mdl-29949257

RESUMO

Chronic periodontitis predictable responds to mechanical cleaning and cause related periodontal surgery. Nowadays the therapeutic protocol of the chronic periodontitis is widely known and scientifically proven. The therapy can be split into two major phases, the inicial or cause related therapy and the surgical therapy, however in the most of the cases the patients need complex periodontal, restorative and prosthodontic therapy. The presented case demonstrates the process and results of the complex treatment of a 55 years old patient suffering from chronic periodontitis. The patient didn't have hopeless teeth. In the first phase of the cause related periodontal therapy professional oral hygiene treatment, scaling rootplaning and subgingival curettage were performed by quadrants. At the re-evaluation after the conservative periodontal therapy there was a significant pocket reduction in the mandibular quadrants, however there was a need for surgical pocket therapy in the molar regions of the maxillary quadrants. Modified Widman-flap surgery and osteoplasty were performed in both of the maxillary quadrants. After the surgical periodontal therapy the revision of the old root canal fillings was accomplished in the teeth 24, 36 and 47. Due to an inflammatory root resorption, root resection was performed following the root canal filling on the tooth 24. Three months after the root resection surgery, the tooth was reinforced by a glass fiber post. Nine months postoperatively the periapical area of the tooth 24 showed growing radioopacity After the second reevaluation of patient's compliance and the healing tendencies full mouth prosthodontic reheabilitation was provided. Metalloceramic crowns with a supragingival margin were made on the teeth 12, 24 and 36, metalloceramic bridge was made on the teeth 44 and 47. After the periodontal, restorative and prosthodontic therapy were finished the patient was remanded every 3 months for periodontal supportive therapy and could maintain excellent oral hygiene with a plaque score under 20% and a bleeding score of 6%.


Assuntos
Periodontite Crônica/terapia , Assistência Odontológica , Raspagem Dentária , Humanos , Pessoa de Meia-Idade , Tratamento do Canal Radicular , Curetagem Subgengival
20.
Clin Oral Implants Res ; 27(7): 845-9, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26374080

RESUMO

BACKGROUND: Non-surgical mechanical therapy of peri-implantitis (PI) with/without adjunctive measures yields limited clinical improvements. AIM: To evaluate the clinical outcomes following non-surgical mechanical therapy of PI with adjunctive application of a diode laser after an observation period ≥2 years. MATERIAL AND METHODS: At baseline (BL), 15 patients with 23 implants with a sandblasted and acid-etched (SLA) surface diagnosed with PI were enrolled and treated. PI was defined as presence of probing pocket depths (PPD) ≥5 mm with bleeding on probing (BoP) and/or suppuration and ≥2 threads with bone loss after delivery of the restoration. Implant sites were treated with carbon fiber and metal curettes followed by repeated application of a diode laser 3x for 30 s (settings: 810 nm, 2.5 W, 50 Hz, 10 ms). This procedure was performed at Day 0 (i.e., baseline), 7 and 14. Adjunctive antiseptics or adjunctive systemic antibiotics were not prescribed. RESULTS: All implants were in function after 2 years. The deepest PPD decreased from 7.5 ± 2.6 mm to 3.6 ± 0.7 mm at buccal (P < 0.0001) and from 7.7 ± 2.1 mm to 3.8 ± 0.9 mm at oral sites (P < 0.0001), respectively. The % of implants with ≥1 site with BoP decreased from 100% at BL to 43% after 2 years (P = 0.0002). The % of implants with suppuration decreased from 87% at BL to 0% after 2 years (P < 0.0001). CONCLUSION: Non-surgical mechanical therapy of PI with adjunctive repeated application of a diode laser yielded significant clinical improvements after an observation period of at least 2 years.


Assuntos
Lasers Semicondutores/uso terapêutico , Peri-Implantite/terapia , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Curetagem Subgengival , Supuração/terapia
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